Analytical Data
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基因名
IZUMO1
- Application
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别名
Folate receptor 4 Folate receptor delta Short name: FR-delta IZUMO1 receptor protein JUNO
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
A6ND01
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表达区间
20-250aa
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分子量
30.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
IZUMO1 is a crucial sperm protein that plays a vital role in the fertilization process, specifically in the fusion of sperm and egg cells. It is primarily expressed on the surface of spermatozoa and interacts with its receptor, Juno, found on the oocyte. Research on IZUMO1 has gained significant attention due to its importance in reproductive biology and its potential applications in fertility treatments and contraception. The study of IZUMO1 recombinant protein involves cloning, expressing, and purifying this protein to understand its structure and function in greater detail. By analyzing the molecular mechanisms behind sperm-egg interaction mediated by IZUMO1, researchers aim to uncover insights that could lead to novel approaches for addressing infertility issues. Additionally, the development of IZUMO1-based contraceptives is being explored, as inhibiting its function could prevent sperm-egg fusion effectively. Overall, the investigation of IZUMO1 recombinant protein represents a significant area of research within reproductive science, with implications for enhancing fertility treatments and providing new methods of contraception.
