Analytical Data
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Gene name
ACBD7
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简介
ACBD7 Protein, pivotal in cellular metabolism, exhibits specific binding to medium- and long-chain acyl-CoA esters, hinting at a role as a molecular carrier for intracellular transport. This unique capability suggests ACBD7's involvement in regulating lipid metabolism, emphasizing its potential impact on cellular processes related to lipid homeostasis and energy metabolism. ACBD7 Protein, Human (His) is the recombinant human-derived ACBD7 protein, expressed by E. coli , with N-His labeled tag.
- Application
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Alternative Names
Acyl-CoA-binding domain-containing protein 7; ACBD7
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 95% as determined by SDS-PAGE.
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Uniprot
Q8N6N7
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Expression Region
M1-I88
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Protein Length
Full Length
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Molecular Weight
10 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ACBD7, or Acyl-CoA Binding Domain Containing 7, is a protein that has garnered significant interest in the scientific community due to its potential roles in lipid metabolism, cellular signaling, and disease pathogenesis. Initially identified as a member of the acyl-CoA binding protein family, ACBD7 has been implicated in various cellular processes, including the regulation of lipid droplet dynamics and the modulation of mitochondrial function. Research indicates that ACBD7 may interact with lipid species and other proteins involved in membrane trafficking and energy metabolism, suggesting its crucial role in maintaining cellular homeostasis. Dysregulation of ACBD7 has been linked to metabolic disorders, including obesity and diabetes, and it may contribute to the pathophysiology of neurodegenerative diseases. As such, understanding the structural and functional properties of ACBD7 through recombinant protein studies is essential for elucidating its mechanisms of action and potential as a therapeutic target. Advances in recombinant DNA technology have enabled the production of ACBD7 in heterologous systems, allowing researchers to explore its biochemical characteristics, interaction partners, and functional implications in greater detail. Overall, the study of ACBD7 not only enhances our understanding of lipid biology but also opens new avenues for therapeutic intervention in metabolic and neurodegenerative diseases.
