Analytical Data
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Gene name
DPP10
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简介
The DPP10 protein is a key regulator that promotes cell surface expression of the potassium channel KCND2, modulating its activity and gating properties. Despite its name, DPP10 lacks dipeptidyl aminopeptidase activity. DPP10 Protein, Human (HEK293, His) is the recombinant human-derived DPP10 protein, expressed by HEK293 , with N-His labeled tag.
- Application
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Alternative Names
Inactive dipeptidyl peptidase 10; DPRP-3; DPP X; DPL2; DPP10
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Species
Human
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Source
HEK293
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N608-1
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Expression Region
L56-E796
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Protein Length
Extracellular Domain
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Molecular Weight
90-110 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DPP10 (Dipeptidyl Peptidase 10) is a member of the dipeptidyl peptidase family, which plays a crucial role in protein metabolism by regulating the activity of various neuropeptides and hormones. Originally identified for its expression in the central nervous system, DPP10 is implicated in several physiological processes, including neuronal signaling and immune responses. Recent studies have shown that DPP10 may be involved in the pathogenesis of certain neurological disorders and psychiatric conditions, such as schizophrenia and epilepsy, due to its regulatory effects on voltage-gated potassium channels. As a result, researchers are increasingly focused on the recombinant production of DPP10 for in-depth functional studies and therapeutic applications. Utilizing techniques such as recombinant DNA technology, scientists aim to produce DPP10 with high purity and activity for use in biochemical assays, structural biology studies, and potential drug development. The ability to generate DPP10 in sufficient quantities allows for investigations into its enzymatic mechanisms, interaction with other proteins, and its role in disease processes. Understanding DPP10's functional aspects could provide valuable insights into its therapeutic potential and lead to new interventions for conditions associated with its dysregulation. Thus, the study of recombinant DPP10 is of paramount importance for expanding our comprehension of its biological significance and its implications in health and disease.
