Analytical Data
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基因名
FBP1
- Application
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别名
FBP1; FBPase 1; Liver FBPase; D-fructose-1,6-bisphosphate 1-phosphohydrolase 1
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P09467
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表达区间
Met1~Gln338
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分子量
67kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FBP1, or Fructose-1,6-bisphosphatase 1, is a key regulatory enzyme in gluconeogenesis, the metabolic pathway that generates glucose from non-carbohydrate precursors. It plays a critical role in maintaining glucose homeostasis, particularly in liver and kidney tissues. Dysregulation of FBP1 has been implicated in metabolic disorders, including diabetes and obesity. Given its importance, recombinant FBP1 protein has become a focal point of research for understanding its biochemical properties and regulatory mechanisms. Producing FBP1 in a recombinant system allows researchers to examine its structure-function relationships, the effects of various allosteric regulators, and the impact of post-translational modifications. Further studies on recombinant FBP1 can provide insights into potential therapeutic targets for metabolic diseases, including strategies to enhance its activity or mitigate its dysfunction. Overall, the research on FBP1 underscores its significance not only in basic biochemistry but also in the development of novel treatments for metabolic conditions.
