Analytical Data
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基因名
CRIPT
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简介
CRIPT is a key member of the small spliceosome and plays a crucial role in U12-type intron splicing, contributing to the complexity of RNA splicing. CRIPT Protein, Human (His) is the recombinant human-derived CRIPT protein, expressed by E. coli , with N-His labeled tag.
- Application
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别名
Cysteine-rich PDZ-binding protein; CRIPT; HSPC139
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9P021
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表达区间
M1-V101
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蛋白长度
Full Length
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分子量
14 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CRIPT (Cytosolic RNA-binding Protein Interacting Protein) is an emerging player in cellular biology, particularly in the context of RNA metabolism and post-transcriptional regulation. It is known to interact with various RNA-binding proteins, thereby influencing mRNA stability, localization, and translation. The study of CRIPT and its recombinant protein forms has gained attention due to its potential roles in critical biological processes such as cell proliferation, differentiation, and stress response. Researchers are interested in understanding how CRIPT interacts with different cellular pathways, especially in relation to diseases such as cancer, where dysregulation of RNA-binding proteins can severely alter gene expression profiles. By developing CRIPT recombinant proteins, scientists aim to elucidate the functional mechanisms of CRIPT and its interactions within the cell, thereby providing insights into its role as a regulatory component in RNA processing and cellular homeostasis. This research is crucial for identifying new therapeutic targets and advancing our understanding of the molecular underpinnings of diseases linked to RNA metabolism dysregulation.
