Analytical Data
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基因名
APOD
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简介
APOD Proteinas is an anti-inflammatory antagonist in the IL-1 family, targeting IL1B and IL1A to prevent immune dysregulation and systemic inflammation. Its ability to modulate inflammatory responses has important implications for potential therapeutic intervention in inflammatory diseases. APOD Protein, Human (HEK293, C-His) is the recombinant human-derived APOD protein, expressed by HEK293 , with C-10*His labeled tag.
- Application
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别名
rHuApolipoprotein D, His; ApoD; Apolipoprotein D
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种属
Human
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表达系统
HEK293
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标签
C-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P05090
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表达区间
Q21-S189
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蛋白长度
Full Length of Mature Protein
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分子量
25-40 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
APOD, or Apolipoprotein D, is a member of the apolipoprotein family, primarily known for its role in lipid metabolism and transport. It has gained significant attention in recent years due to its implications in various physiological and pathological processes, including neurodegenerative diseases, cancer, and metabolic disorders. APOD's ability to bind and transport lipids suggests it may play a crucial role in maintaining cellular homeostasis and influencing signaling pathways. Research into the structural and functional aspects of recombinant APOD protein has been crucial in uncovering its mechanisms of action and potential therapeutic applications. By employing techniques such as X-ray crystallography and nuclear magnetic resonance, scientists aim to elucidate the protein's three-dimensional structure, which is vital for understanding its function at the molecular level. Moreover, the development of recombinant APOD allows for the study of its interactions with other biomolecules, advancing our knowledge of its role in health and disease. These studies not only provide insight into APOD's biological functions but also open avenues for its potential use as a biomarker or therapeutic target in conditions where its expression is altered. Understanding APOD's role could lead to innovative strategies in treating diseases linked with lipid dysregulation and neuroinflammation, thereby highlighting the importance of this protein in biomedical research.
