Analytical Data
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基因名
FGFR-1 alpha
- Application
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别名
Basic fibroblast growth factor receptor 1 (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD_antigen: CD331) (FGFR-1) (BFGFR) (CEK) (FGFBR) (FLG) (FLT2) (HBGFR)
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P11362
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表达区间
156-376aa
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分子量
28.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Fibroblast growth factor receptor 1 (FGFR-1) plays a crucial role in various biological processes, including cell proliferation, differentiation, and survival. It is part of the FGFR family, which is involved in signaling pathways that regulate development and tissue homeostasis. Abnormalities in FGFR-1 signaling are implicated in several diseases, notably various cancers and congenital disorders. The study of FGFR-1 alpha, which is a splice variant of FGFR-1, has garnered attention due to its specific roles in oncogenesis and cell signaling. Recombinant FGFR-1 alpha protein has emerged as a valuable tool for investigating its functional properties and interactions with ligands, as well as its downstream signaling pathways. Understanding the structure and function of FGFR-1 alpha at a molecular level can provide insights into its role in health and disease. Additionally, it may facilitate the development of targeted therapeutic strategies aimed at modulating FGFR-1 activity in pathological conditions. Due to its significance in various signaling cascades, the recombinant FGFR-1 alpha protein is of great interest in both basic research and clinical applications, especially in the context of targeted cancer therapies and regenerative medicine. As researchers continue to explore the functionalities of FGFR-1 alpha, this protein may offer novel biomarkers or therapeutic targets, advancing the field of precision medicine and improving patient outcomes.
