Analytical Data
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基因名
Fetuin B
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简介
Fetub Protein, a glycoprotein, plays a significant role in regulating insulin sensitivity and lipid metabolism. Dysregulation of Fetub Protein has been associated with several diseases, including obesity and type 2 diabetes. Fetuin B Protein, Mouse (HEK293, His) is the recombinant mouse-derived Fetuin B protein, expressed by HEK293 , with C-His labeled tag.
- Application
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别名
Fetuin-B; 16G2; Fetuin-Like Protein IRL685; Gugu; FETUB
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种属
Mouse
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表达系统
HEK293
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标签
C-His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
Q9QXC1
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表达区间
R19-P388
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氨基酸序列
RSPPAPPLPQRPLSPLHPLGCNDSEVLAVAGFALQNINRDQKDGYMLSLNRVHDVREHYQEDMGSLFYLTLDVLETDCHVLSRKAQKDCKPRMFYESVYGQCKAMFHINKPRRVLYLPAYNCTLRPVSKRKTHTTCPDCPSPIDLSNPSALEAATESLAKFNSKSPSKKYELVKVTKAMNQWVSGPAYYVEYLIKEAPCTKSQASCSLQHSDSEPVGICQGSTVQSSLRHVPLIQPVEKSVTVTCEFFESQAQVPGDENPAVTQGPQKLPQKNTAPTSSPSVTAPRGSIQHLPELDDEKPEESKGGSPEEAFPVQLDLTTNPQGDTLDVSFLYLEPGDKKLVVLPFPGKEQRSAECPGPEKENNPLVLPP
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蛋白长度
Full Length of Mature Protein
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分子量
55-65 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Fetuin B, a member of the fetuin family of glycoproteins, has garnered attention due to its significant role in metabolic processes and physiological functions. Initially identified as a serum protein predominantly produced in the liver, Fetuin B is implicated in regulating lipid metabolism and insulin sensitivity. Its expression has been linked to various metabolic disorders, including obesity and type 2 diabetes, making it a potential biomarker for these conditions. Recent studies have highlighted its function in modulating inflammation and understanding its molecular mechanisms may unveil new therapeutic approaches for metabolic diseases. The recombinant production of Fetuin B offers opportunities to study its structure-function relationships more effectively and to explore its interactions with other biomolecules in detail. Moreover, the ability to produce this protein in significant quantities is crucial for developing assays and interventions targeting Fetuin B's pathways. By elucidating these pathways, researchers hope to clarify the protein's multifaceted role in metabolism, paving the way for innovative treatments for obesity-related disorders and beyond.
