Cat: IPD-X25684

Recombinant Dog Annexin A13/ANXA13 Protein (HEK293),His

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Analytical Data

  • Gene name

    Annexin A13/ANXA13

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Annexin XIII Annexin-13 Intestine-specific annexin Short name: ISA

  • Species

    Dog

  • Source

    HEK293

  • Tag

    N- His

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q29471

  • Expression Region

    2-316aa

  • Molecular Weight

    39.3 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Annexin A13 (ANXA13) is a member of the annexin family of proteins, which are characterized by their ability to bind to phospholipids in a calcium-dependent manner. This protein plays a pivotal role in various cellular processes, including membrane trafficking, cell signaling, and apoptosis. Research has indicated that ANXA13 is involved in the regulation of endocytosis and exocytosis, which are crucial for maintaining cellular homeostasis. Additionally, ANXA13 has been linked to several pathological conditions, including cancer, where its expression levels may correlate with tumor progression and metastasis. The study of recombinant ANXA13 proteins has gained importance in the field of molecular biology, as these proteins can be utilized to explore the functional mechanisms underlying its role in cellular processes. By producing recombinant ANXA13 in heterologous expression systems, researchers aim to investigate its structural properties, interaction with other cellular components, and potential as a therapeutic target. This research not only enhances our understanding of ANXA13's biological functions but also paves the way for developing novel strategies for disease treatment, particularly in contexts where ANXA13 expression is dysregulated. The ongoing exploration of ANXA13 through recombinant protein studies holds promise for advancing both basic research and translational applications in medical science.

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