Cat: IPD-X38098

Recombinant Human TAOK1 Protein (Baculovirus),His & GST

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Analytical Data

  • Gene name

    TAOK1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    TAOK1; TAO kinase 1; DDIB; PSK2; TAO1; KFC-B; MARKK; PSK-2; hKFC-B; hTAOK1; MAP3K16

  • Species

    Human

  • Source

    Baculovirus

  • Tag

    His;GST

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q7L7X3-1

  • Expression Region

    P2-K314

  • Protein Length

    Partial

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

TAOK1, or T-cell activation protein 1, is a member of the TAO (thyroid and embryonic aster) family of serine/threonine kinases, which play crucial roles in various cellular processes, including cell growth, differentiation, and apoptosis. Recent studies have highlighted the significance of TAOK1 in neural development and its potential link to neurological disorders such as autism and schizophrenia. TAOK1 is known to be involved in the regulation of the MAPK signaling pathway, which is essential for cellular responses to a variety of stimuli. Additionally, mutations and dysregulation of TAOK1 expression have been implicated in several diseases, prompting researchers to investigate its role in cellular signaling and disease pathology. The study of TAOK1 recombinant proteins provides valuable insights into its structure and function, facilitating the elucidation of its biochemical pathways and interactions. By producing and analyzing TAOK1 recombinant proteins, scientists aim to better understand the mechanisms underlying its involvement in neurodevelopmental processes and its potential as a therapeutic target in related disorders. The ongoing research on TAOK1 not only enhances our fundamental knowledge of kinase-mediated signaling but also opens avenues for developing novel interventions in the treatment of diseases associated with TAOK1 dysregulation.

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