Recombinant Mouse AIF1 Protein (HEK293)，hFc

AIF1, or Allograft Inflammatory Factor 1, is a protein that plays a significant role in the immune response, particularly in macrophage activation and inflammation. Initially identified in the context of allograft rejection, AIF1 has garnered attention for its involvement in various pathological conditions, including autoimmune diseases, cancer, and neurodegenerative disorders. Research has demonstrated that AIF1 is upregulated in inflammatory conditions and is associated with the polarization of macrophages towards a pro-inflammatory phenotype. Its ability to regulate cell migration and survival further complicates its role in inflammation and tissue repair. The recombinant expression of AIF1 as a fusion protein has facilitated studies aimed at elucidating its functional mechanisms and interactions at the molecular level. By producing AIF1 in a recombinant form, researchers can assess its impact on immune cell behavior and explore potential therapeutic applications, such as targeting AIF1 for modulating immune responses. Understanding the precise biological functions of AIF1 and its signaling pathways could provide insights into developing novel strategies for treating inflammation-related diseases and improving transplant outcomes. Overall, AIF1 remains a key focus for researchers interested in the interplay between immunity and inflammation, highlighting its potential as a biomarker and therapeutic target in diverse medical fields.