Analytical Data
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Gene name
Lymphocyte antigen 6E/LY6E
- Application
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Alternative Names
LY6E; 9804; RIGE; SCA2; TSA1; Lymphocyte antigen 6E; Ly-6E; Retinoic acid-induced gene E protein; RIG-E; Stem cell antigen 2; SCA-2; Thymic shared antigen 1; TSA-1
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Species
Human
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Source
HEK293
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Tag
C-hFc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q16553
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Expression Region
L21-S101
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Protein Length
Full Length of Mature Protein
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Molecular Weight
40-43 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Lymphocyte antigen 6E (LY6E) is a member of the LY6 family of glycosylphosphatidylinositol (GPI)-anchored proteins, which play pivotal roles in immune responses. Research has indicated that LY6E is involved in various biological processes, including T cell activation, proliferation, and differentiation. Notably, LY6E has been implicated in the immune response to viral infections, as it can modulate signaling pathways that influence the activation and function of immune cells. Its expression is typically enhanced in activated lymphocytes, suggesting a critical role in adaptive immunity. The study of recombinant LY6E protein has gained interest for its potential to serve as a therapeutic target or biomarker in autoimmune diseases and infections. By producing and characterizing recombinant LY6E protein, researchers aim to elucidate its functional mechanisms and interactions with other molecules in the immune system. This understanding can pave the way for novel immunotherapeutic strategies that leverage LY6E for enhancing immune responses against pathogens or tumors. Furthermore, exploring the structure-function relationship of LY6E through recombinant techniques can provide insights into its role in immune modulation, ultimately contributing to advancements in immunology and therapeutic development.
