Analytical Data
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Gene name
MRCKG
- Application
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Species
Human
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Source
Baculovirus
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Tag
Tag Free
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6DT37
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Expression Region
M1-G475
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MRCKG, or Myotonic Dystrophy Kinase Related CDC42 Binding Kinase Gamma, is a member of the MRCK family of serine/threonine kinases that play crucial roles in cell migration, proliferation, and cytoskeletal dynamics. Research into MRCKG has gained momentum due to its significant involvement in various cellular processes and its association with diseases such as cancer and neurodegenerative disorders. This protein is particularly noteworthy for its ability to interact with the small GTPase CDC42, a key regulator of actin cytoskeleton remodeling. The reorganization of the cytoskeleton is fundamental for various cellular functions that include cell shape maintenance and motility. Investigating MRCKG's role in these processes could unveil novel pathways and therapeutic targets for diseases characterized by altered cell migration and proliferation. Additionally, the development of recombinant MRCKG proteins allows for in-depth studies of its biochemical properties, interaction networks, and regulatory mechanisms. By analyzing the structure and function of MRCKG, researchers aim to elucidate its precise role in cellular signaling and its potential implications in pathophysiological contexts. This research not only contributes to our fundamental understanding of cellular biology but also holds promise for developing targeted therapies that combat diseases involving aberrant cellular behaviors. The ongoing studies into MRCKG's functions and regulatory mechanisms continue to reveal intricate details about its role in health and disease, highlighting the importance of this kinase in both basic and applied biomedical research.
