Analytical Data
-
基因名
AKT2
-
简介
The AKT2 protein is a serine/threonine protein kinase in the AKT family that is critical for metabolism, proliferation, survival, growth, and angiogenesis. It phosphorylates more than 100 substrates, coordinates insulin-induced SLC2A4/GLUT4 translocation, affects glucose uptake, and controls glycogen storage. AKT2 Protein, Human (Active, sf9, GST) is the recombinant human-derived AKT2, expressed by Sf9 insect cells, with GST labeled tag. The total length of AKT2 Protein, Human (Active, sf9, GST) is 480 a.a..
- Application
-
种属
Human
-
表达系统
Baculovirus
-
标签
GST
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P31751
-
表达区间
N2-E481
-
蛋白长度
Partial
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
AKT2, a member of the AKT family of serine/threonine kinases, plays a critical role in various cellular processes, including metabolism, growth, proliferation, and survival. It is activated in response to insulin and growth factors, making it integral to signaling pathways that regulate glucose homeostasis and cellular response to stress. Dysregulation of AKT2 has been associated with several diseases, particularly type 2 diabetes and various cancers, highlighting its potential as a therapeutic target. Understanding the structure and function of AKT2 is essential for developing targeted treatments. The study of recombinant AKT2 protein allows researchers to explore its biochemistry, interaction with other molecules, and regulatory mechanisms. This can pave the way for novel strategies to manipulate AKT2 activity in disease contexts. Advances in protein engineering and expression systems have enabled the production of active AKT2, facilitating further investigations into its role in cell signaling and its implications in metabolic diseases and tumor biology. Overall, the research into AKT2 recombinant protein serves as a foundation for future therapeutic developments aimed at correcting the imbalances associated with its dysfunction.
