Analytical Data
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基因名
Apolipoprotein C-III/APOC3
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简介
Apolipoprotein C-III (APOC3) is a component of VLDL and HDL and plays a crucial role in triglyceride homeostasis. Intracellularly, it facilitates the assembly and secretion of VLDL1 for lipid transport. Apolipoprotein C-III/APOC3 Protein, Mouse (His-SUMO) is the recombinant mouse-derived Apolipoprotein C-III/APOC3 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
- Application
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别名
Apoc3Apolipoprotein C-III; Apo-CIII; ApoC-III; Apolipoprotein C3
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种属
Mouse
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表达系统
E. coli
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标签
N-6*His;N-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P33622
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表达区间
E21-S99
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蛋白长度
Full Length of Mature Protein
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分子量
22 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Apolipoprotein C-III (ApoC-III) is a key component of lipoproteins and plays a crucial role in lipid metabolism and cardiovascular health. It is primarily synthesized in the liver and intestines and is known to inhibit lipoprotein lipase, thereby affecting triglyceride clearance from the bloodstream. Elevated levels of ApoC-III have been linked to an increased risk of dyslipidemia and cardiovascular diseases. As such, studying the biochemical properties and functions of ApoC-III is vital for understanding its role in lipid disorders and developing therapeutic strategies. Recombinant ApoC-III protein has become a valuable tool in research, allowing scientists to investigate its physiological effects and interactions with other lipoproteins in a controlled environment. By producing this protein through recombinant DNA technology, researchers can examine its effects on lipid metabolism, explore potential inhibitors, and assess its implications in diseases related to cholesterol and triglyceride metabolism. Consequently, the understanding of ApoC-III through recombinant protein studies may not only elucidate its biological functions but also contribute to innovative approaches in the treatment of lipid-related diseases.
