Analytical Data
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Gene name
PNCK
- Application
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Alternative Names
CaMK1b; Pregnancy Upregulated Non-Ubiquitously Expressed CaM Kinase; Calcium/calmodulin-dependent protein kinase type 1B
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6P2M8
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Expression Region
Ile68~Trp343
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Molecular Weight
35kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PNCK (p41Nop56/Nop58 complex) is a member of the cyclin-dependent kinase (CDK) family, playing a significant role in cell cycle regulation and various cellular processes. Its importance has been underscored in recent years due to its potential involvement in oncogenesis, as aberrant expression of PNCK has been linked to several types of cancer. The study of PNCK recombinant proteins is critical for understanding its biochemical properties, regulatory mechanisms, and interactions with other cellular proteins. Recombinant PNCK can be utilized in various experimental settings, such as crystallography and binding assays, to elucidate its structure-function relationship. Investigating PNCK through recombinant techniques also enables the development of specific inhibitors that could serve as therapeutic agents. Furthermore, the exploration of PNCK's role in cellular pathways and its interaction with CDK inhibitors might reveal novel insights into cancer biology and identify potential biomarkers for tumor progression. Overall, the research on PNCK recombinant proteins can pave the way for innovative approaches to cancer treatment, emphasizing the need for continued exploration in this promising field.
