Analytical Data
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基因名
PRKCZ
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简介
PKCz proteins are involved in multiple cellular processes, including mitotic signaling, cell proliferation, cell polarity, inflammatory responses, and maintenance of long-term potentiation (LTP). PRKCZ Protein, Human (sf9, GST) is the recombinant human-derived PKCz protein, expressed by sf9 insect cells , with N-GST labeled tag.
- Application
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别名
PRKCZ; Protein kinase C zeta type; nPKC-zeta
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种属
Human
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表达系统
Baculovirus
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标签
N-GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q05513-1
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表达区间
P2-V592
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蛋白长度
Partial
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PRKCZ, or Protein Kinase C Zeta, is a member of the protein kinase C (PKC) family, which plays a crucial role in cellular signaling, including regulation of cell growth, differentiation, and apoptosis. The importance of PRKCZ in various biological processes has generated significant interest in its function and regulation, especially in the context of cancer and neurodegenerative diseases. Abnormal expression or activity of PRKCZ has been implicated in several pathologies, marking it as a potential therapeutic target. Researchers have focused on the production of recombinant PRKCZ protein to better understand its structure, function, and interactions at the molecular level. The use of recombinant protein allows for detailed biochemical assays, structural studies, and the exploration of potential inhibitors. Techniques such as site-directed mutagenesis and molecular modeling have been employed to elucidate the mechanisms of PRKCZ action and its role in signal transduction pathways. Understanding PRKCZ's functions and regulatory mechanisms is essential not only for uncovering its role in disease but also for potential therapeutic interventions designed to modulate its activity. As our knowledge of PRKCZ expands, it holds promise for advancing our understanding of related signaling networks and developing novel strategies for disease treatment.
