Analytical Data
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Gene name
HLA-B
- Application
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Alternative Names
/
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Species
Human
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96DW9
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Expression Region
25-308aa
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Molecular Weight
36.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HLA-B (Human Leukocyte Antigen B) is a crucial component of the major histocompatibility complex (MHC) class I molecules, playing a significant role in the immune response by presenting endogenous peptides to CD8+ T cells. The research on HLA-B recombinant proteins has gained prominence due to their essential role in transplantation biology, disease susceptibility, and vaccine development. The polymorphic nature of HLA-B genes, with numerous alleles that can impact individual immune responses, makes it vital to understand their structure and function. Recombinant HLA-B proteins can be utilized for a variety of applications, including the study of T cell recognition, the development of HLA-based therapies, and the potential for personalized medicine. Additionally, they serve as valuable tools in understanding autoimmune diseases and infectious disease responses, as specific HLA-B alleles have been linked to resistance or susceptibility to certain conditions. As researchers continue to unravel the complexities of the immune system, the production and functional analysis of HLA-B recombinant proteins stand at the forefront, facilitating insights into immunological mechanisms and paving the way for innovative therapeutic approaches.
