Analytical Data
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基因名
SRXN1
- Application
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种属
Human
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BYN0
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表达区间
1-137aa
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分子量
19.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SRXN1 (sulfiredoxin 1) is a crucial redox-regulating enzyme that plays a significant role in cellular defense against oxidative stress by reducing hyperoxidized peroxiredoxins back to their active forms. Its study has gained momentum due to its implications in various pathological conditions, including cancer, neurodegenerative diseases, and cardiovascular disorders. Elevated levels of reactive oxygen species (ROS) are associated with the onset and progression of these diseases, making SRXN1 a potential target for therapeutic interventions aimed at modulating redox homeostasis. Research has shown that SRXN1 is not only involved in protecting cells from oxidative damage but also plays a role in promoting cell survival and proliferation under stress conditions. Understanding the molecular mechanisms underlying its action can provide insights into novel strategies for enhancing cellular resilience. Additionally, the recombinant expression of SRXN1 in various systems allows for in-depth functional studies and the development of SRXN1-based therapeutic approaches. By producing and characterizing SRXN1 recombinant proteins, researchers aim to investigate its enzymatic properties, interaction with other redox-active proteins, and its biological significance in both normal and disease states. This research could pave the way for innovative treatments that harness SRXN1’s protective effects, contributing to improved outcomes in diseases where oxidative stress is a contributing factor.
