Analytical Data
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Gene name
TXLNA
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简介
The TXLNA protein may be involved in intracellular vesicle trafficking, specifically calcium-dependent exocytosis in neuroendocrine cells. Its binding kinetics involve interactions with the C-terminal coiled-coil region of synaptophysin family members such as STX1A, STX3A, and STX4A. TXLNA Protein, Human (His) is the recombinant human-derived TXLNA protein, expressed by E. coli , with N-6*His, C-6*His labeled tag.
- Application
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Alternative Names
Alpha-Taxilin; TXLNA; TXLN
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Species
Human
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Source
E. coli
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Tag
N-6*His;C-6*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P40222
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Expression Region
M1-K162
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Protein Length
Partial
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Molecular Weight
30.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TXLNA (translin-associated protein) is a protein implicated in various cellular processes, including RNA binding and regulation. Its study has gained attention due to its potential role in neural development, cellular signaling, and gene expression regulation. Recent advances in molecular biology have facilitated the exploration of TXLNA's functions and interactions, particularly its involvement in neurogenesis and synaptic plasticity. Researchers are interested in TXLNA's ability to influence RNA metabolism and its possible link to neurological disorders. Understanding the structure and function of TXLNA through recombinant protein techniques can provide insights into its biological roles and therapeutic implications, particularly in conditions such as autism spectrum disorders and other neurodevelopmental conditions. The recombinant expression of TXLNA allows scientists to study its biochemical properties, elucidate its interactions with other molecular partners, and explore its potential as a target for drug development. By employing techniques such as protein purification and functional assays, researchers aim to uncover the mechanisms by which TXLNA contributes to cellular and molecular dynamics in the nervous system, offering pathways toward novel therapeutic strategies.
