Analytical Data
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基因名
RBP1
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简介
RBP1 Protein, a cytoplasmic retinol-binding protein, functions in retinol uptake, storage, and retinoid homeostasis by accepting retinol from the transport protein STRA6. The interaction between RBP1 and STRA6 occurs specifically in the retinol-free apoprotein state. RBP1 Protein, Human is the recombinant human-derived RBP1 protein, expressed by E. coli , with tag free.
- Application
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别名
Retinol-binding protein 1; Cellular retinol-binding protein; CRBP; Cellular retinol-binding protein I; CRBP-I; RBP1; CRBP1
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种属
Human
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表达系统
E. coli
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标签
Tag Free
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P09455
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表达区间
P2-Q135
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蛋白长度
Partial
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分子量
14.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RBP1, or Retinoblastoma Binding Protein 1, is a crucial component in the regulation of gene expression and cellular processes, primarily known for its role in cell cycle control and tumor suppression. Research into RBP1 has gained significance due to its implication in various cancers, particularly retinoblastoma, where mutations in the RBP1 gene contribute to tumorigenesis. The recombinant expression of RBP1 provides valuable insights into its functional mechanisms, allowing scientists to dissect its interactions with other proteins, explore its role in cellular signaling pathways, and assess its potential as a therapeutic target. Advances in molecular biology techniques, particularly in recombinant DNA technology, have facilitated the production of RBP1 in heterologous systems, enabling the purification and characterization of the protein. This research not only enhances our understanding of RBP1’s biological functions but also opens avenues for developing novel cancer treatments that leverage its tumor-suppressive properties or correct its dysregulations in cancer cells. Consequently, the study of recombinant RBP1 holds promise for both basic research and clinical applications, furthering our knowledge of cancer biology and improving therapeutic strategies.
