Analytical Data
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基因名
PRAP1
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简介
Proline-rich acidic protein 1 (PRAP1) is a lipid-binding protein which promotes lipid absorption; negatively regulates the apoptotic process; gets involved in p53/TP53-dependent cell survival after DNA damage; causes cell cycle arrest; maintains normal growth homeostasis in epithelial cells and suppress mitotic spindle assembly checkpoint in hepatocellular carcinomas. PRAP1 Protein, Human (HEK293, His) is the recombinant human-derived PRAP1 protein, expressed by HEK293 , with C-6*His labeled tag.
- Application
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别名
Proline-Rich Acidic Protein 1; Epididymis Tissue Protein Li 178; Uterine-Specific Proline-Rich Acidic Protein; PRAP1; UPA
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种属
Human
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表达系统
HEK293
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标签
C-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96NZ9
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表达区间
V21-Q151
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蛋白长度
Full Length of Mature Protein
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分子量
20.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PRAP1 (Proline-Rich Acidic Protein 1) is a regulatory protein that has garnered significant interest in recent years due to its potential role in various cellular processes, including cell signaling, proliferation, and differentiation. Identified initially in the context of muscle development, PRAP1 has been implicated in the regulation of stress responses and cellular adaptations under various physiological conditions. Research indicates that PRAP1 may interact with multiple signaling pathways, influencing the activity of key transcription factors and contributing to the modulation of gene expression. The recombination and expression of PRAP1 as a recombinant protein have enabled scientists to study its functional properties in detail, providing insights into its molecular mechanisms and potential applications in therapeutic contexts. Understanding PRAP1’s role at the molecular level could lead to novel strategies for manipulating its activity in diseases where its function is compromised. Additionally, the development of PRAP1-based biosensors or therapeutic agents highlights the protein's significance in both basic research and potential clinical applications, paving the way for future studies that could explore its utility in regenerative medicine and cancer therapy.
