Analytical Data
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Gene name
Mucin-13
- Application
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Alternative Names
DRCC1; RECC; Down-Regulated In Colon Cancer 1
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H3R2
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Expression Region
Ser174~Gln404
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Molecular Weight
29kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Mucin-13 (MUC13) is a member of the mucin family, characterized by heavily glycosylated glycoproteins that play critical roles in protecting epithelial cells and modulating various biological processes, including cell signaling, adhesion, and immune response. Elevated expression of MUC13 has been implicated in several cancers, particularly in colorectal and pancreatic cancers, where it contributes to tumor progression and metastasis. The protein's unique structure, with a large extracellular domain and a transmembrane domain, renders it a potential target for therapeutic interventions. Despite its importance, the functional mechanisms and signaling pathways involving MUC13 remain poorly understood, partly due to challenges in obtaining recombinant MUC13 proteins for experimental studies. Recent advances in recombinant protein technology have enabled the production of MUC13, allowing researchers to investigate its biological functions and interactions in greater detail. Understanding MUC13's role in cancer biology could lead to novel diagnostic markers and therapeutic strategies, emphasizing the need for comprehensive studies of this protein within the context of disease progression and treatment response.
