Analytical Data
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基因名
ATP6V0D1
- Application
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别名
V-type proton ATPase subunit d 1; V-ATPase subunit d 1; 32 kDa accessory protein; V-ATPase 40 kDa accessory protein; V-ATPase AC39 subunit (p39); Vacuolar proton pump subunit d 1
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种属
Human
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表达系统
E. coli
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标签
N-GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P61421
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表达区间
M1-F351
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蛋白长度
Full Length
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ATP6V0D1, a crucial subunit of the vacuolar H+-ATPase (V-ATPase) complex, plays a significant role in cellular processes, particularly in acidifying intracellular compartments and regulating various physiological functions. V-ATPases are multi-subunit enzymes responsible for transporting protons across membranes, thereby affecting pH levels and ion homeostasis within cells. Perturbations in ATP6V0D1 expression or function have been linked to several pathophysiological conditions, including cancer, neurodegenerative diseases, and metabolic disorders. Emerging research indicates that ATP6V0D1 may influence the migration and invasion of cancer cells, making it a potential target for therapeutic interventions. The ability to produce recombinant ATP6V0D1 protein is crucial for investigating its structural properties, enzymatic functions, and interactions with other cellular partners. This research not only enhances our understanding of ATP6V0D1’s role in normal physiology but also underscores its potential implications in disease contexts, paving the way for novel treatment strategies.
