Analytical Data
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基因名
MTCP1
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简介
The MTCP1 protein plays a crucial role in promoting the phosphorylation and activation of AKT1 and AKT2, two key members of the AKT family. It does this through specific interactions with AKT1 and AKT2, primarily through their PH (pleckstrin homology) domains. MTCP1 Protein, Human (His, Strep) is the recombinant human-derived MTCP1 protein, expressed by E. coli , with N-Strep, N-6*His labeled tag.
- Application
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别名
MTCP1; Protein p13 MTCP-1; p13MTCP1; Mature T-cell proliferation-1 type B1; MTCP-1 type B1
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种属
Human
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表达系统
E. coli
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标签
N-StrepⅡ;N-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P56278
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表达区间
M1-D107
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蛋白长度
Full Length
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MTCP1 (Mouse T-Cell Receptor Gene Protein 1) is a crucial protein involved in the regulation of T-cell development and function. Originally identified in murine models, MTCP1 has drawn attention due to its role in various immune responses and its potential implications in autoimmune diseases and lymphoproliferative disorders. Research has shown that MTCP1 expression is prominently associated with certain types of leukemias and lymphomas, highlighting its importance as a biomarker for these conditions. Additionally, the study of MTCP1 has expanded into understanding its molecular structure and interactions within the immune system, which may unveil novel therapeutic strategies for targeting T-cell-related diseases. The reconstitution of MTCP1 as a recombinant protein allows for detailed investigations into its functional properties and interactions with other cellular components, facilitating the exploration of its roles in both health and disease. Understanding the mechanisms by which MTCP1 operates could provide valuable insights into T-cell biology and aid in the development of innovative immunotherapies.
