Analytical Data
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基因名
MMP-10
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简介
MMP-10 protein is a member of the matrix metalloproteinase family and plays a crucial role in extracellular matrix remodeling by promoting the degradation of various substrates. As a protease, MMP-10 is involved in tissue homeostasis, wound healing, and inflammatory responses. MMP-10 Protein, Human (P. pastoris, His) is the recombinant human-derived MMP-10 protein, expressed by P. pastoris , with N-6*His labeled tag.
- Application
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种属
Human
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表达系统
P. pastoris
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标签
N-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P09238
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表达区间
F99-C476
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氨基酸序列
FSSFPGMPKWRKTHLTYRIVNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPGHSLAHAYPPGPGLYGDIHFDDDEKWTEDASGTNLFLVAAHELGHSLGLFHSANTEALMYPLYNSFTELAQFRLSQDDVNGIQSLYGPPPASTEEPLVPTKSVPSGSEMPAKCDPALSFDAISTLRGEYLFFKDRYFWRRSHWNPEPEFHLISAFWPSLPSYLDAAYEVNSRDTVFIFKGNEFWAIRGNEVQAGYPRGIHTLGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQGFPRLIADDFPGVEPKVDAVLQAFGFFYFFSGSSQFEFDPNARMVTHILKSNSWLHC
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蛋白长度
Full Length of Mature Protein
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分子量
45 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Matrix metalloproteinase-10 (MMP-10), also known as stromelysin-2, is a crucial enzyme involved in the degradation of extracellular matrix components and plays a significant role in various physiological and pathological processes, including tissue remodeling, wound healing, and inflammatory responses. Overexpression of MMP-10 has been implicated in several diseases, such as cancer metastasis, cardiovascular diseases, and chronic inflammatory conditions. Research into MMP-10 has garnered attention due to its potential as a biomarker for disease progression and its viability as a therapeutic target. Recombinant MMP-10 protein production has facilitated detailed studies of its structure, function, and interaction with other molecules, providing valuable insights into its regulatory mechanisms. Understanding the role of MMP-10 in disease processes could lead to innovative strategies for treatment and prevention. Moreover, the development of MMP-10 inhibitors might offer novel therapeutic options for conditions characterized by excessive matrix degradation. The ongoing exploration of MMP-10's functions through recombinant technologies emphasizes its relevance in biomedical research, paving the way for new interventions that leverage this enzyme's unique properties.
