Analytical Data
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基因名
KCTD1
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简介
KCTD1 protein is a potential transcriptional regulator that inhibits AP-2 family members (TFAP2A, TFAP2B, TFAP2C). The formation of its homodimer indicates self-association, while the interaction with AP-2 members through the BTB domain emphasizes its role in complex molecular interactions. KCTD1 Protein, Human (sf9, His, Strep) is the recombinant human-derived KCTD1 protein, expressed by sf9 insect cells , with N-Strep, N-8*His labeled tag.
- Application
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别名
KCTD1; BTB/POZ domain-containing protein KCTD1; Potassium channel tetramerization domain-containing protein 1
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种属
Human
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表达系统
Baculovirus
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标签
N-StrepⅡ;N-8*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q719H9
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表达区间
S2-D257
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蛋白长度
Partial
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KCTD1, or Potassium Channel Tetramerization Domain 1, is a protein that plays a significant role in various cellular processes, including ion channel regulation and signal transduction. It is characterized by the presence of a KCTD domain, which is involved in the assembly and function of potassium channels. Recent studies have suggested that KCTD1 might be implicated in several physiological and pathological conditions, such as neurodevelopmental disorders and certain cancers, due to its regulatory functions in cellular signaling pathways. The elucidation of the structure and function of KCTD1 is essential for understanding its biological roles and potential as a therapeutic target. Moreover, recombinant KCTD1 protein production has opened new avenues for researching its interactions with other proteins and its impact on potassium channel activity. Investigating KCTD1 through recombinant technology allows researchers to manipulate and study the protein in-depth, paving the way for the development of novel treatments for diseases associated with potassium channel dysfunction. Understanding the mechanisms by which KCTD1 exerts its effects at the molecular level is critical for harnessing its potential in biomedical applications.
