Analytical Data
-
基因名
PSMG3
-
简介
The PSMG3 protein acts as a chaperone and actively promotes the assembly of the 20S proteasome. It involves potential cooperation with the PSMG1-PSMG2 heterodimer to ensure precise assembly of the proteasome. PSMG3 Protein, Human is the recombinant human-derived PSMG3 protein, expressed by E. coli , with tag free.
- Application
-
别名
PSMG3; Proteasome assembly chaperone 3; PAC-3; hPAC3
-
种属
Human
-
表达系统
E. coli
-
标签
Tag Free
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9BT73
-
表达区间
M1-W122
-
蛋白长度
Full Length
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PSMG3, or proteasome subunit gamma 3, is a vital component of the 26S proteasome, a multi-subunit complex responsible for the degradation of ubiquitinated proteins, playing a crucial role in maintaining cellular homeostasis. Research into PSMG3 has intensified due to its implications in various biological processes, including cell cycle regulation, apoptosis, and immune response. Dysregulation of the proteasome system has been linked to several diseases, including cancer and neurodegenerative disorders. Understanding the structure and function of PSMG3 is essential for elucidating its role in proteasomal function. Recent studies have employed advanced techniques such as X-ray crystallography and cryo-electron microscopy to explore the conformational dynamics of PSMG3, revealing insights into its interactions within the proteasome framework. Additionally, investigations into PSMG3's post-translational modifications are shedding light on its regulatory mechanisms. As the demand for targeted therapies grows, PSMG3 presents a potential therapeutic target, making its study increasingly pertinent in the context of drug development and disease treatment strategies. The ongoing research aims not only to delineate the molecular functions of PSMG3 but also to harness this knowledge for biomedical applications, underscoring its significance in the landscape of molecular biology and therapeutic innovation.
