Cat: IPD-X29226

Recombinant Cynomolgus TPSAB1 Protein,His

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Analytical Data

  • 基因名

    TPSAB1

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Tryptase alpha/beta-1; Tryptase-1; Tryptase I; Tryptase alpha-1; TPS1; TPS2; TPSB1

  • 种属

    Cynomolgus

  • 表达系统

    E. coli

  • 标签

    N-8*His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    XP_005590891.2

  • 表达区间

    I38-P282

  • 蛋白长度

    Partial

  • 分子量

    30-33kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

TPSAB1, or Tryptase Beta 1, is a serine protease predominantly expressed in mast cells, playing a critical role in various physiological and pathological processes, including allergic responses, inflammation, and tissue remodeling. Research has highlighted its multifaceted involvement in immune system modulation and its potential impact on diseases such as asthma, atopic dermatitis, and anaphylaxis. Given that TPSAB1 is released from activated mast cells, it can influence the behavior of other immune cells and contribute to the inflammatory milieu in various tissues. The study of TPSAB1 recombinant proteins is significant for understanding its enzymatic properties, substrate specificity, and interactions with other proteins involved in the inflammatory cascade. Moreover, these recombinant proteins serve as valuable tools for developing therapeutic interventions targeting mast cell-related disorders. The exploration of TPSAB1's structure and function could lead to novel treatment strategies for conditions characterized by excessive mast cell activation and dysfunction, thereby addressing a pressing need in clinical immunology and allergy research. As such, TPSAB1 has emerged as a promising candidate for further investigation, laying the groundwork for advancements in targeted therapies and enhancing our overall understanding of mast cell biology and its implications in human health.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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