Analytical Data
-
基因名
Casein Kinase I alpha
- Application
-
别名
CSNK1-A1; CK1; HLCDGP1
-
种属
Rat
-
表达系统
E. coli
-
标签
N-His
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P97633
-
表达区间
Leu114~Gly324
-
分子量
28kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Casein Kinase I alpha (CK1α) is a serine/threonine kinase that plays a crucial role in various cellular processes, including cell cycle regulation, DNA repair, and circadian rhythms. It is involved in several signaling pathways, such as the Wnt and Hedgehog pathways, which are pivotal in development and cancer progression. Dysregulation of CK1α has been linked to numerous diseases, particularly cancer, making it a promising target for therapeutic intervention. The study of recombinant CK1α proteins has gained significant interest due to their potential in elucidating the protein's function, studying its enzymatic mechanisms, and screening for inhibitors. By producing CK1α through recombinant DNA technology, researchers can obtain large quantities of the protein, allowing for detailed biochemical and structural studies. Understanding the regulation and activity of CK1α at a molecular level is essential for developing CK1α-targeted therapies and investigating its role in various pathological conditions. This research not only enhances our knowledge of CK1α's biological functions but also paves the way for innovative strategies in drug design and development in the context of cancer and other diseases.
