Analytical Data
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Gene name
ENPP-3
- Application
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Alternative Names
CD203c; CD203-c; B10; NPP3; PD-IBETA; PDNP3; Phosphodiesterase I beta; Alkaline phosphodiesterase I; Nucleotide pyrophosphatase
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6DYE8
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Expression Region
Leu595~Ile874
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Molecular Weight
39kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ENPP-3, or ecto-nucleotide pyrophosphatase/phosphodiesterase 3, is a member of the ENPP family of enzymes, which primarily function in hydrolyzing nucleotide substrates and regulating extracellular nucleotide signaling. The research on ENPP-3 has gained significance due to its involvement in various physiological and pathological processes, including bone mineralization, inflammatory responses, and tumor progression. It has been shown that ENPP-3 plays a crucial role in modulating the levels of extracellular ATP and other nucleotides, thus influencing cell communication and signaling pathways. Dysregulation of ENPP-3 has been implicated in several diseases, including cancer and bone disorders, making it a potential therapeutic target. The production of recombinant ENPP-3 protein allows for detailed biochemical characterization and provides insights into its enzymatic mechanisms and substrate specificity. Furthermore, the availability of this enzyme in a purified form facilitates the exploration of its functional roles in cellular environments and the development of inhibitors or modulators that could have clinical applications in treating related diseases. Overall, the study of ENPP-3 and its recombinant protein holds promise for advancing our understanding of nucleotide metabolism and its implications in health and disease.
