Analytical Data
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基因名
CORS26
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简介
CORS26 Protein is a secreted protein of the C1q/ TNF-associated protein (CTRPs) family. CORS26 Protein involved in the LAMP1-STAT3, SIRT1/NF-魏B/p53, NF-魏B and TGF-尾1/Smad3 pathways play anti-inflammatory effects. CORS26 Protein also inhibited the expression of antimicrobial peptide (CAMP) in adipocytes induced by toll-like receptors (TLR). CORS26 Protein, Mouse (Myc, His) is the recombinant mouse-derived CORS26 protein, expressed by E. coli , with N-His, C-Myc labeled tag.
- Application
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别名
C1qtnf3; Cors26; Ctrp3; Complement C1q tumor necrosis factor-related protein 3; Collagenous repeat-containing sequence 26kDa protein; CORS26; Secretory protein CORS26
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种属
Mouse
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表达系统
E. coli
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标签
N-His;C-Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9ES30
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表达区间
Q23-K246
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氨基酸序列
QDEYMESPQAGGLPPDCSKCCHGDYGFRGYQGPPGPPGPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPRGERGQHGPKGEKGYPGVPPELQIAFMASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFTFSMMKHEDVEEVYVYLMHNGNTVFSMYSYETKGKSDTSSNHAVLKLAKGDEVWLRMGNGALHGDHQRFSTFAGFLLFETK
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蛋白长度
Full Length of Mature Protein
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分子量
31.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CORS26, a protein associated with cellular stress responses and longevity, has garnered significant attention in the field of molecular biology and aging research. Discovered in various model organisms, including yeast and nematodes, CORS26 appears to play a crucial role in regulating autophagy, a cellular process responsible for degrading and recycling damaged organelles and proteins. Research indicates that CORS26 levels can influence lifespan and stress resistance, suggesting that it may serve as a biomarker for cellular health and aging. Furthermore, preliminary studies suggest that modifications to CORS26 expression could potentially enhance autophagic activity, offering a promising avenue for therapeutic interventions aimed at age-related diseases and metabolic disorders. Ongoing investigations seek to unravel the precise mechanisms by which CORS26 exerts its effects on cellular homeostasis, including its interactions with other key regulatory proteins and its role in signaling pathways. Understanding CORS26's function could provide insights into novel strategies for promoting healthy aging and developing interventions against age-related pathologies.
