Cat: IPD-X29117

Recombinant Human Claudin-6 Protein (HEK293),His & GFP

  • Price
  • Size
  • Number

    Order now. For delivery time, please consult customer service

  • Pre-sale guidance and worry-free after-sale service
  • Quality assurance for cold chain transportation

Analytical Data

  • Gene name

    Claudin-6

  • 简介

    Claudin-6/CLDN6 Protein-VLP is pivotal in targeted elimination of intercellular spaces within tight junctions, ensuring cell barrier integrity and polarity. Moreover, it serves as a receptor for hepatitis C virus (HCV), facilitating viral entry into hepatic cells. Claudin-6 Protein-Nanodisc, Human (HEK293, GFP, His) is the recombinant human-derived Claudin-6 protein, expressed by HEK293, with C-His and C-GFP labeled tag.

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    Claudin-6; Skullin; CLDN6; Claudin6; Skullin 2

  • Species

    Human

  • Source

    HEK293

  • Tag

    C-His;C-GFP

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P56747-1

  • Expression Region

    M1-V220

  • Protein Length

    Full Length of Isoform-1

  • Molecular Weight

    37.2 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

Related Products

Protein Description

Claudin-6 is a member of the claudin family of proteins, which are critical components of tight junctions in epithelial cells. These proteins play a crucial role in maintaining cellular integrity by regulating paracellular permeability and enabling selective barrier functions within tissues. Recent studies have highlighted Claudin-6's involvement in various physiological processes and its potential implications in disease, particularly in cancer. Notably, Claudin-6 is overexpressed in certain malignancies, including ovarian and gastric cancers, making it a focal point for targeted therapies and immunotherapeutic strategies. The recombinant production of Claudin-6 provides a valuable tool for investigating its role in tumor biology and for developing diagnostic and therapeutic applications. Understanding the structural and functional characteristics of Claudin-6 can aid in elucidating its mechanisms of action and reveal novel insights for clinical use. Research on Claudin-6 also highlights the broader significance of tight junction proteins in maintaining cellular homeostasis and their potential utility in regenerative medicine and tissue engineering. Overall, Claudin-6 remains an intriguing subject for further exploration due to its dual utility in understanding basic cellular processes and advancing therapeutic interventions in cancer treatment.

E-mail

sales@ipodix.com

Sales

+1 2092920560


Contact us via WhatsApp

IPODIX Biotech Inc

2108 N ST, STE N
Sacramento, CA 95816, USA

For Product Information and Orders

sales@ipodix.com

For Business Collaboration

sales@ipodix.com

For CRO Services

sales@ipodix.com

For Technical Support

sales@ipodix.com
  • 50000+

    Recombinant Proteins

  • 100+

    Researchers

  • 100+

    Countries Served

  • ISO

    Certified Quality

Committed to Quality
Driven by Innovation

Learn More About US