Analytical Data
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基因名
DPP3
- Application
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种属
Rat
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表达系统
E. coli
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标签
Strep;His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O55096
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表达区间
M1-A738
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蛋白长度
Full Length
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Dipeptidyl peptidase III (DPP3) is a membrane-bound enzyme that plays a crucial role in the metabolism of bioactive peptides and is implicated in various physiological processes, including blood pressure regulation and neuropeptide processing. Its involvement in health and disease has attracted significant research interest, particularly in the context of cardiovascular and neurodegenerative disorders. DPP3 is known to exhibit peptidase activity, contributing to the inactivation of a range of peptides such as angiotensin II and substance P, which are key regulators of cardiovascular function and neuronal signaling, respectively. Recent studies have suggested that DPP3 may also be linked to inflammatory responses and cancer progression, highlighting its potential as a therapeutic target. The development of recombinant DPP3 protein allows for in-depth biochemical characterization and facilitates the exploration of its substrate specificity and inhibitor design, which is critical for understanding its role in pathophysiological conditions. Furthermore, generating a stable and active form of DPP3 through recombinant techniques provides a valuable tool for drug discovery and the development of novel therapeutic strategies aimed at modulating its activity for clinical benefits. As research on DPP3 continues to evolve, the recombinant protein holds promise for unraveling the complexities of its biological functions and therapeutic potential.












