Analytical Data
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Gene name
OTULIN
- Application
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Alternative Names
FAM105B
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Species
Human
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Source
E. coli
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Tag
His;GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96BN8
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Expression Region
M1-L352
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Protein Length
Full Length
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
OTULIN, a member of the A20 protein family, functions as a deubiquitinating enzyme that plays a critical role in regulating immune responses and maintaining cellular homeostasis. Given its involvement in the removal of ubiquitin chains from modified proteins, OTULIN is essential for controlling inflammation and apoptosis pathways. Research has shown that mutations or dysregulation of OTULIN are linked to various autoimmune diseases and conditions characterized by chronic inflammation, underscoring its importance in human health. Recent studies have aimed to elucidate the structural and functional aspects of OTULIN, paving the way for potential therapeutic strategies targeting its pathways to mitigate autoimmune disorders and improve patient outcomes. As such, the recombinant production of OTULIN has become a focal point for understanding its biological mechanisms and developing targeted interventions. This research not only enhances our fundamental knowledge of ubiquitination processes but also holds promise for innovative treatments in immunological diseases.
