Analytical Data
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Gene name
OTUD3
- Application
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Alternative Names
KIAA0459
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Species
Human
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Source
E. coli
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Tag
Tag Free
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5T2D3
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Expression Region
E52-D209
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
OTUD3 is a deubiquitinating enzyme that belongs to the ovarian tumor domain (OTU) family and has gained attention in recent years due to its critical roles in cellular processes such as protein degradation, signal transduction, and stress responses. Ubiquitination is a post-translational modification that regulates protein stability and function, and the removal of ubiquitin chains by deubiquitinating enzymes (DUBs) is essential for maintaining cellular homeostasis. OTUD3 specifically targets ubiquitinated proteins and plays a significant role in modulating various signaling pathways, including those involved in immune response and cell cycle regulation. Research has shown that OTUD3 can influence the stability and activity of key proteins such as p53 and NF-kB, thereby impacting tumorigenesis and cellular stress responses. Additionally, OTUD3 has been implicated in several diseases, including cancer and neurodegenerative disorders, making it a potential therapeutic target. Understanding the molecular mechanisms by which OTUD3 acts is essential for developing new strategies for disease intervention. Therefore, the study of OTUD3 recombinant protein not only provides insights into its functional role and structural characteristics but also highlights its potential in translational applications. As the field of proteomics and targeted therapies advances, OTUD3 stands out as a promising candidate for future research aimed at harnessing its DUB activity for therapeutic benefits.
