Analytical Data
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基因名
PDGFA
- Application
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别名
PDGF-A; PDGF1; Platelet Derived Growth Factor Alpha Polypeptide
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
P20033
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表达区间
Glu90~Glu190
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分子量
15kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PDGFA (Platelet-Derived Growth Factor A) is a crucial growth factor that plays a significant role in various biological processes, including cell proliferation, survival, and migration, as well as tissue repair and development. Initially identified for its involvement in platelet granules, PDGFA exerts its functions primarily through binding to its receptor, PDGFR-α, influencing a wide range of cellular responses. Research on PDGFA has gained momentum due to its implications in several pathological conditions, such as fibrotic diseases, cancer, and vascular abnormalities. The recombinant production of PDGFA has facilitated the detailed study of its biological activities and mechanisms of action, enabling scientists to explore its potential therapeutic applications. Utilizing recombinant DNA technology, PDGFA can be produced in large quantities and with high purity, allowing for in-depth analyses of its properties and interactions with receptors. Understanding the structure-function relationship of PDGFA is pivotal for designing targeted therapies, particularly in oncology and regenerative medicine. Furthermore, the recombinant protein serves as a valuable tool for investigating the signaling pathways activated by PDGFA and its role in tumor microenvironment interactions. As such, ongoing research endeavors aim to elucidate the multifaceted roles of PDGFA and leverage its properties for novel therapeutic strategies.












