Analytical Data
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Gene name
HCoV-OC43
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简介
HCoV-OC43 is a type of coronavirus 1 that infects humans and cattle. HCoV-OC43 forms a spiky structural protein on the surface of the virus, contains receptor binding and receptor destruction activities, and mediates the deacetylation of n-acetyl-4-o-acetylneuraminic acid. HCoV-OC43 Hemagglutinin esterase Protein (HEK293, His) is the recombinant Virus-derived HCoV-OC43 Hemagglutinin esterase protein, expressed by HEK293 , with C-His labeled tag.
- Application
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Alternative Names
Human coronAvirus (HCoV-OC43) Hemagglutinin esterase Protein (His)
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Species
Virus
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Source
HEK293
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Tag
C-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
APU51943
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Expression Region
L17-P394
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
HCoV-OC43, a member of the human coronavirus family, is one of the causative agents of respiratory infections, particularly in children and immunocompromised individuals. As a beta-coronavirus, it has gained attention due to its role in seasonal outbreaks and its impact on public health. Research into its recombinant proteins has become increasingly important for understanding the virus's biology, pathogenesis, and immune response. Recombinant proteins, especially the spike (S) protein, play a crucial role in virus entry into host cells and are essential for the development of diagnostic tools, therapeutics, and vaccines. The study of HCoV-OC43 recombinant proteins facilitates the identification of epitopes that are crucial for neutralizing antibodies, thereby aiding in vaccine design. Moreover, this research provides insights into the evolutionary dynamics of coronaviruses, especially in the context of emerging strains and the potential for interspecies transmission. As the world continues to grapple with coronavirus-related diseases, understanding HCoV-OC43 and its recombinant proteins could offer valuable knowledge for addressing current challenges and preparing for future outbreaks.
