Analytical Data
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基因名
HCoV-OC43
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简介
HCoV-OC43 is a type of coronavirus 1 that infects humans and cattle. HCoV-OC43 forms a spiky structural protein on the surface of the virus, contains receptor binding and receptor destruction activities, and mediates the deacetylation of n-acetyl-4-o-acetylneuraminic acid. HCoV-OC43 Hemagglutinin esterase Protein (HEK293, His) is the recombinant Virus-derived HCoV-OC43 Hemagglutinin esterase protein, expressed by HEK293 , with C-His labeled tag.
- Application
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别名
Human coronAvirus (HCoV-OC43) Hemagglutinin esterase Protein (His)
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种属
Virus
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表达系统
HEK293
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标签
C-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
APU51943
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表达区间
L17-P394
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蛋白长度
Partial
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HCoV-OC43, a member of the human coronavirus family, is one of the causative agents of respiratory infections, particularly in children and immunocompromised individuals. As a beta-coronavirus, it has gained attention due to its role in seasonal outbreaks and its impact on public health. Research into its recombinant proteins has become increasingly important for understanding the virus's biology, pathogenesis, and immune response. Recombinant proteins, especially the spike (S) protein, play a crucial role in virus entry into host cells and are essential for the development of diagnostic tools, therapeutics, and vaccines. The study of HCoV-OC43 recombinant proteins facilitates the identification of epitopes that are crucial for neutralizing antibodies, thereby aiding in vaccine design. Moreover, this research provides insights into the evolutionary dynamics of coronaviruses, especially in the context of emerging strains and the potential for interspecies transmission. As the world continues to grapple with coronavirus-related diseases, understanding HCoV-OC43 and its recombinant proteins could offer valuable knowledge for addressing current challenges and preparing for future outbreaks.
