Analytical Data
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基因名
PLA2G12B
- Application
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别名
Group XIIB phospholipase A2-like protein
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种属
Mouse
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表达系统
HEK293
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标签
C-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8VC81
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表达区间
Q20-L195
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蛋白长度
Full Length of Mature Protein
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分子量
24 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PLA2G12B (phospholipase A2 group 12B) is a member of the phospholipase A2 family, which plays a crucial role in various physiological processes, including inflammation, cell signaling, and membrane remodeling. This enzyme is known to hydrolyze phospholipids, generating bioactive lysolipids that can modulate cellular responses. The interest in PLA2G12B has surged due to its potential implications in various diseases, including cancer and cardiovascular disorders. Research has shown that aberrations in phospholipase activity may contribute to the pathogenesis of these conditions, making this enzyme a target for therapeutic intervention. Recombinant PLA2G12B protein has been produced to facilitate detailed studies of its structure, function, and biochemical properties. Understanding the specific mechanisms of action of PLA2G12B can lead to the identification of novel biomarkers and therapeutic targets. Furthermore, studying this protein in various model systems can elucidate its role in cellular processes and disease models, providing insights into its therapeutic potential. As the field advances, ongoing research aims to explore the biochemical pathways associated with PLA2G12B, paving the way for the development of innovative strategies to manipulate its activity for clinical benefit.
