Analytical Data
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Gene name
ACPL2
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简介
The ACPL2 protein plays a critical role in the regulation of glycosaminoglycan (GAG) chains by catalyzing the 2-O-dephosphorylation of xylose in proteoglycans. This step is critical for the synthesis of sulfated GAGs, including heparan sulfate and chondroitin sulfate. ACPL2 Protein, Human (HEK293, His) is the recombinant human-derived ACPL2 protein, expressed by HEK293 , with C-His labeled tag.
- Application
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Alternative Names
2-phosphoxylose phosphatase 1; Acid phosphatase-like protein 2; PXYLP1; HEL124
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Species
Human
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Source
HEK293
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Tag
C-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8TE99-1
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Expression Region
M1-F480
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Protein Length
Full Length of Isoform-1
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Molecular Weight
50 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ACPL2, also known as "Acidic Cationic Protein-Like 2," has garnered attention in recent years due to its potential implications in various biological processes and diseases. This protein is a member of the cationic protein family, which plays critical roles in immune responses, inflammation, and cellular signaling. Research has indicated that ACPL2 may be involved in the regulation of metabolic pathways, particularly those associated with lipid metabolism and insulin sensitivity. Dysregulation of ACPL2 has been linked to several metabolic disorders, including obesity and type 2 diabetes, prompting further investigation into its functional role. The elucidation of ACPL2's structure and function can provide insights into its mechanism of action and potential therapeutic targets. Additionally, the development of recombinant ACPL2 protein has facilitated studies aimed at understanding its molecular interactions and biological effects. These studies are essential for exploring ACPL2 as a biomarker for disease progression or response to treatment, highlighting the significance of this protein in both basic and translational research. As such, ongoing investigations into ACPL2 are crucial for unveiling its full potential in health and disease management, paving the way for novel therapeutic strategies that could mitigate the impact of metabolic and inflammatory conditions.
