Analytical Data
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Gene name
EMMPRIN/CD147
- Application
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Species
Human
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Source
HEK293
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Tag
C-8*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
NP_940991
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Expression Region
A22-H205
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Protein Length
Partial
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Molecular Weight
28-40 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
EMMPRIN, also known as CD147, is a glycoprotein that plays a crucial role in cellular communication, particularly in cancer progression and tissue remodeling. It is predominantly expressed on the surface of various cell types, including tumor cells, immune cells, and endothelial cells. EMMPRIN is recognized for its ability to induce the production of matrix metalloproteinases (MMPs) in surrounding fibroblasts, facilitating tumor invasion and metastasis. Recent studies have highlighted its involvement in various pathological processes, including inflammation, fibrosis, and angiogenesis, making it a significant player in multiple diseases beyond cancer. The recombinant protein of EMMPRIN/CD147 has garnered attention as a potential therapeutic target due to its pivotal role in tumor microenvironment dynamics. Additionally, understanding the structure and function of this protein can provide insights into the mechanisms of cell-cell interactions and the extracellular matrix's role in disease progression. Research efforts are currently focused on exploring the therapeutic implications of EMMPRIN modulation, with the aim of developing novel strategies for cancer treatment and other related diseases. Given its multifaceted biological functions, EMMPRIN/CD147 stands out as a promising candidate for future research endeavors in both basic and translational science.
