Analytical Data
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Gene name
TBCK
- Application
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Alternative Names
FERRY1; TBCKL
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Species
Human
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Source
Baculovirus
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Tag
His;GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8TEA7-1
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Expression Region
F2-I893
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of TBCK (TBC1 domain family, member 5) recombinant proteins has garnered increasing attention in recent years due to their significant roles in cellular processes and potential implications in various diseases. TBCK is a member of the TBC (Tre-2/BUB2/CDC16) domain family, which is known for its involvement in regulating the RAB GTPases, crucial for intracellular vesicle trafficking and membrane dynamics. Dysregulation of TBCK has been linked to several pathologies, including neurodevelopmental disorders and certain cancers, highlighting the necessity for a deeper understanding of its molecular mechanisms. By producing recombinant TBCK protein, researchers aim to elucidate its functional properties, interactions with other cellular proteins, and its impact on GTPase activity. Moreover, characterizing TBCK at the structural and functional levels can pave the way for developing therapeutic strategies targeting its pathways. The availability of recombinant TBCK also facilitates high-throughput screening for small molecules that modulate its activity, contributing to drug discovery efforts. Overall, the exploration of TBCK recombinant proteins is pivotal for advancing our comprehension of its biological roles and therapeutic potential in treating diseases associated with its dysfunction.
