Analytical Data
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基因名
VEGF-B
- Application
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别名
VEGF-related factor ;VRF
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种属
Human
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表达系统
Yeast
-
标签
N- His
-
纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P49765
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表达区间
22-207aa
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蛋白长度
Partial
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分子量
21.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Vascular Endothelial Growth Factor B (VEGF-B) is a member of the VEGF family known for its crucial role in mediating angiogenesis, the formation of new blood vessels from pre-existing ones, and for supporting the survival of endothelial cells. Unlike its better-studied counterparts, VEGF-A and VEGF-C, which are primarily involved in promoting blood vessel formation and lymphangiogenesis, VEGF-B has garnered attention for its unique functions in regulating metabolic processes and neuronal protection. Research indicates that VEGF-B plays a significant role in cardiovascular health, as it is involved in the development and maintenance of the cardiac and vascular systems. Furthermore, studies have suggested that VEGF-B may influence lipid metabolism and facilitate the delivery of fatty acids to tissues, highlighting its potential implications in metabolic disorders and diseases such as obesity and diabetes. Given its diverse biological functions, the recombinant protein form of VEGF-B has been explored as a therapeutic agent with promising applications in tissue engineering and regenerative medicine. Researchers are increasingly focused on elucidating the mechanisms of VEGF-B signaling pathways and its interactions with other growth factors, aiming to harness its potential for innovative treatments in vascular-related diseases and enhancing the efficacy of existing therapies. Understanding the nuanced role of VEGF-B in both normal physiology and disease states is critical for developing targeted strategies to manipulate angiogenic processes and improve outcomes in various clinical conditions.












