Cat: IPD-X28701

Recombinant Others Heparinase Protein,Strep & His

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Analytical Data

  • 基因名

    Heparinase

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    heparin-sulfate lyase HepC

  • 种属

    Others

  • 表达系统

    E. coli

  • 标签

    Strep;His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    WP_041517255.1

  • 表达区间

    A22-L658

  • 蛋白长度

    Partial

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Heparinase is an important glycosidase enzyme that specifically degrades heparin and heparan sulfate, which are sulfated glycosaminoglycans involved in various biological processes, including cell signaling, coagulation, and inflammation. The study of Heparinase, particularly recombinant forms of the enzyme, has gained considerable attention in biomedical research due to its potential therapeutic applications. By producing Heparinase as a recombinant protein, researchers can obtain a more stable, efficient, and pure source of the enzyme for various studies. This is particularly relevant in the context of developing novel anticoagulant therapies or understanding the roles of heparan sulfate in various diseases, such as cancer and cardiovascular disorders. The ability to generate high quantities of recombinant Heparinase opens new avenues for both fundamental research into the mechanisms of glycosaminoglycan interactions and for the practical application of Heparinase in enzyme-based therapies. Furthermore, understanding the structure-function relationships of this enzyme can lead to enhancements in its activity and specificity, paving the way for innovative drug design strategies targeting heparin-related pathways. This research not only aims to elucidate the biochemical properties of Heparinase but also explores its clinical implications, thereby contributing to the broader field of glycobiology and therapeutics.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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