Analytical Data
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Gene name
NCL
- Application
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Alternative Names
C23; Protein C23
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 95% as determined by SDS-PAGE.
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Uniprot
P09405
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Expression Region
Tyr353~Ser568
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Molecular Weight
28kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NCL (Nucleolin) is a multifunctional protein that plays a crucial role in various cellular processes, including ribosome biogenesis, cell proliferation, and regulation of gene expression. Its overexpression has been linked to several cancers, making it a potential therapeutic target. The study of recombinant NCL proteins has surged in recent years, driven by the need to better understand its structural and functional properties. Recombinant protein technology allows researchers to produce NCL in a controlled environment, enabling detailed studies of its interactions with nucleic acids and other binding partners. These investigations not only enhance our understanding of NCL's role in normal cellular functions but also provide insights into its implications in cancer biology. Additionally, the ability to create specific NCL variants through recombinant techniques facilitates the exploration of targeted therapies and diagnostic tools. Overall, the research on recombinant NCL proteins represents a significant area of interest that could lead to innovative approaches for cancer treatment and potentially other diseases involving aberrant NCL signaling.
