Analytical Data
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Gene name
MIZ1
- Application
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Alternative Names
BTB domain-containing protein; Chlorocebus sabaeus; Green monkey
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Species
Others
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Source
E. coli
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Tag
Strep;His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
A0A0D9S8H5
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Expression Region
M1-S116
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MIZ1, or Myc Interacting Zinc Finger Protein 1, is a vital transcription factor involved in various cellular processes, including cell proliferation, differentiation, and apoptosis. Its role in cancer biology has attracted significant attention due to its interaction with the Myc oncogene, which is known to drive tumorigenesis in multiple cancer types. Research has indicated that MIZ1 can act as a transcriptional repressor, modulating the expression of genes crucial for tumor progression and maintenance. The study of recombinant MIZ1 proteins has gained momentum, as they can be utilized to dissect the molecular mechanisms underlying its function and interactions within the cellular environment. By producing MIZ1 in a recombinant form, researchers can investigate its structural properties, binding affinities, and the effects of its post-translational modifications. Furthermore, the recombinant protein can be used in therapeutic contexts to develop MIZ1-targeted strategies for cancer treatment or as a tool in drug discovery to identify compounds that can modulate its activity. Understanding MIZ1’s role at the molecular level is essential for elucidating its contributions to oncogenesis and for exploring its potential as a biomarker or therapeutic target in malignancies where Myc and related pathways are dysregulated. Overall, the investigation of MIZ1 through recombinant proteins facilitates a deeper understanding of its biological functions and paves the way for novel approaches in cancer therapeutics.
