Analytical Data
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基因名
MIZ1
- Application
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别名
BTB domain-containing protein; Chlorocebus sabaeus; Green monkey
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种属
Others
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表达系统
E. coli
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标签
Strep;His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
A0A0D9S8H5
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表达区间
M1-S116
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蛋白长度
Partial
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MIZ1, or Myc Interacting Zinc Finger Protein 1, is a vital transcription factor involved in various cellular processes, including cell proliferation, differentiation, and apoptosis. Its role in cancer biology has attracted significant attention due to its interaction with the Myc oncogene, which is known to drive tumorigenesis in multiple cancer types. Research has indicated that MIZ1 can act as a transcriptional repressor, modulating the expression of genes crucial for tumor progression and maintenance. The study of recombinant MIZ1 proteins has gained momentum, as they can be utilized to dissect the molecular mechanisms underlying its function and interactions within the cellular environment. By producing MIZ1 in a recombinant form, researchers can investigate its structural properties, binding affinities, and the effects of its post-translational modifications. Furthermore, the recombinant protein can be used in therapeutic contexts to develop MIZ1-targeted strategies for cancer treatment or as a tool in drug discovery to identify compounds that can modulate its activity. Understanding MIZ1’s role at the molecular level is essential for elucidating its contributions to oncogenesis and for exploring its potential as a biomarker or therapeutic target in malignancies where Myc and related pathways are dysregulated. Overall, the investigation of MIZ1 through recombinant proteins facilitates a deeper understanding of its biological functions and paves the way for novel approaches in cancer therapeutics.
