Cat: IPD-X28681

Recombinant Human VEGF165 Protein,His

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Analytical Data

  • 基因名

    VEGF165

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 95% as determined by SDS-PAGE.

  • 蛋白编号

    P15692

  • 表达区间

    Pro28~Arg191

  • 分子量

    20kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Vascular endothelial growth factor (VEGF) is a key signaling protein that primarily regulates angiogenesis, the formation of new blood vessels from pre-existing ones. Among its isoforms, VEGF165 is the most abundant and biologically active variant, playing a critical role in both normal physiological processes and various pathological conditions, such as cancer, diabetes, and eye diseases like age-related macular degeneration. The study of VEGF165 recombinant protein has gained significant attention due to its potential applications in therapeutic interventions and regenerative medicine. Understanding the structure and function of VEGF165 can facilitate the development of VEGF inhibitors for anti-cancer strategies or VEGF-based therapies to promote tissue regeneration and repair. Moreover, investigations into VEGF165's interactions with its receptors offer insights into the underlying molecular mechanisms of angiogenesis and vascular permeability. The recombinant production of VEGF165 allows for the exploration of its effects in controlled experimental settings, paving the way for innovative treatment modalities targeting VEGF-mediated pathways. As such, ongoing research into VEGF165 holds promise for advancing our knowledge of vascular biology and enhancing therapeutic options for diseases characterized by abnormal angiogenesis.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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