Analytical Data
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Gene name
TMEM175
- Application
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Alternative Names
Endosomal/lysosomal proton channel TMEM175; Potassium channel TMEM175; Transmembrane protein 175; hTMEM175; TMEM175; Homo sapiens; Human; Ion channel; Potassium channel
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Species
Human
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Source
HEK293
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Tag
His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BSA9-1
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Expression Region
M1-C504
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Protein Length
Full Length of Isoform-1
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TMEM175 is a member of the transmembrane protein family that has garnered attention due to its potential role in cellular processes and disease mechanisms. Initially discovered through genomic studies, TMEM175 is primarily expressed in various tissues, including the brain, where it is thought to be involved in ion transport and maintaining cellular homeostasis. Recent research has indicated that TMEM175 may be linked to neurological disorders and could play a role in the regulation of autophagy and lysosomal function. Understanding the structure and function of TMEM175 is crucial for elucidating its biological significance and its potential implications in health and disease. The production of recombinant TMEM175 protein has become a focal point for researchers aiming to investigate its properties and interactions in vitro. By generating this recombinant protein, scientists can study its biophysical characteristics, functional assays, and potential therapeutic applications. Overall, the exploration of TMEM175 through recombinant protein studies represents a promising avenue for advancing our understanding of its roles in cellular mechanisms and its impact on various pathophysiological conditions.
