Analytical Data
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Gene name
PLA2G16
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简介
The PLA2G16 protein has dual functions, acting as a phospholipase to exert calcium-independent PLA1 and PLA2 activities, preferentially releasing fatty acids through PLA1. It also acts as an O-acyltransferase and N-acyltransferase, helping to form N-acylphosphatidylethanolamine (the precursor of N-acylethanolamine). PLA2G16 Protein, Human (His) is the recombinant human-derived PLA2G16 protein, expressed by E. coli , with N-6*His labeled tag.
- Application
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Species
Human
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Source
E. coli
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Tag
N-6*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P53816
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Expression Region
D12-D132
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Protein Length
Partial
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Molecular Weight
14-17 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PLA2G16, or Phospholipase A2 Group 16, is a member of the phospholipase A2 family, which plays a crucial role in the metabolism of phospholipids, influencing various cellular processes such as membrane dynamics, inflammation, and signal transduction. Research on PLA2G16 has gained momentum due to its potential implications in diseases like cancer, neurodegenerative disorders, and inflammatory diseases. The enzyme is thought to be involved in the generation of bioactive lipids that can modulate cellular functions and immune responses. Furthermore, studies suggest that PLA2G16 may interact with various signaling pathways and could be a target for therapeutic interventions. Recombinant PLA2G16 protein is often produced for laboratory studies to elucidate its structure-function relationships, explore its enzymatic properties, and investigate its role in cellular contexts. The successful expression and purification of this protein have enabled researchers to delve into its biochemical characteristics and potential applications in drug design and development. Overall, understanding PLA2G16's function and regulation could provide valuable insights into its role in health and disease, paving the way for novel therapeutic strategies.
