Analytical Data
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Gene name
ABCF3
- Application
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Alternative Names
ATP-binding cassette sub-family F member 3; ABCF3; Homo sapiens; Human
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Species
Human
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Source
HEK293
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Tag
Strep;His;Flag
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NUQ8-1
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Expression Region
A2-L709
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Protein Length
Full Length of Mature Protein
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ABCF3, or ATP-binding cassette sub-family F member 3, is a member of the ATP-binding cassette (ABC) transporter family, which plays a crucial role in various cellular processes, including the transport of lipids, drugs, and metabolites across cellular membranes. The study of ABCF3 has gained attention due to its implications in cellular defense mechanisms, particularly in response to xenobiotic stress and the development of multidrug resistance in cancer cells. Unlike other ABC transporters, ABCF3 does not possess the typical transmembrane domains but is known to function in the regulation of protein synthesis and cellular signaling. Research has shown that ABCF3 can modulate the activity of other ABC transporters and is involved in the autophagic degradation of damaged proteins, thereby influencing cell survival and growth. Given its unique functional characteristics and potential role in disease processes, including cancer and neurodegenerative disorders, the recombinant production of ABCF3 protein facilitates in-depth studies on its structure, function, and interactions with other proteins. Understanding the molecular mechanisms by which ABCF3 operates could provide valuable insights into its therapeutic potential and contribute to the development of strategies to overcome drug resistance in cancer treatment. Consequently, exploring ABCF3 not only advances fundamental biological knowledge but also presents opportunities for innovative therapeutic interventions in various diseases.
